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Scientist - Cell Line Products

Horizon is the leading life science company supplying research tools to organisations engaged in genomics research and the development of personalised medicines.  The Company is a trusted supplier of genetically-defined cell lines, reporter gene assay kits, genomic reference standards and contract research services to organizations engaged in bio-pharmaceutical process optimization, drug discovery & development, and clinical diagnostic development. Horizon aspires to provide science-driven research solutions that lead to the advancement in the understanding of the genetic basis of disease and the delivery of better healthcare outcomes for patients.

We have a great opportunity for scientist with cell culture knowledge and some demonstrable hands on experience to join our team to contribute to the validation of Cell Line Products.

Key responsibilities:

Molecular validation of Cell Line products. You will be responsible for assay design, DNA and RNA extraction, and genotyping ensuring on target gene editing events.

You will also culture and cryopreserve mammalian cells using aseptic technique. Testing, inventory, and supplying Cell Banks to internal and external groups.

Core Skills:

  • Strong molecular biology skills including gDNA and RNA isolation, PCR (gDNA, RT-PCR, ddPCR).
  • A good understanding of genetics.
  • Mammalian cell culture experience, with good aseptic technique.
  • Ability to work independently, contributing to experimental design and troubleshooting.
  • Excellent interpersonal and communication skills, both written and verbal.
  • Other responsibilities include authoring technical documents and SOPs.
  • Housekeeping duties in the laboratory including stock management is also a pivotal part of this role.
  • Provide regular updates to leadership team

Experience:

You will  either degree educated or equivalent in cell or molecular biology with up to 2 years proven practical experience.

Possess strong practical laboratory experience of tissue culture, maintaining suspension and adherent cell lines, ideally in industrial setting.

 Experience with molecular biology techniques including DNA/RNA/protein isolation and PCR would be beneficial.

You should be comfortable working in a fast-paced, team environment and on multiple projects with constantly changing priorities and deadlines, be well organized, self-motivated and have excellent communication skills and attention to detail.

In return we offer a varied and interesting working environment and we are focused on recognition and empowerment of our scientists and operational teams and a competitive salary and benefits package, including:

Group Personal Pension Plan with enhanced company contribution
Medical, Health & Life Insurances
Employee share purchase plan (Sharesave) 
25 days annual leave
One paid working day each year for volunteering
Childcare vouchers

 

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